죽염이 염증성 치은섬유모세포에 미치는 영향
Effect of bamboo salt on human gingival fibroblasts
오한나, 최충호,
소속 상세정보
오한나 ( Oh Han-Na ) - 원광보건대학교 치위생과
최충호 ( Choi Choong-Ho ) - 전남대학교 치의학전문대학원 예방치과학교실
KMID : 0355420140380020090
Abstract
Objectives: To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt.
Methods: Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1b and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction.
Results: Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1b secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration.
Conclusions: The above results suggest that bamboo salt inhibits the release of IL-1b and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
키워드
Bamboo salt;Human gingival fibroblast;IL-1b;IL-6
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